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The CYP2C8 inhibitor trimethoprim increases the plasma concentrations of repaglinide in healthy subjects

AIMS: Our aim was to investigate the effect of the CYP2C8 inhibitor trimethoprim on the pharmacokinetics and pharmacodynamics of the antidiabetic drug repaglinide, and to examine the influence of the former on the metabolism of the latter in vitro. METHODS: In a randomized, double-blind, crossover s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Niemi, Mikko, Kajosaari, Lauri I, Neuvonen, Mikko, Backman, Janne T, Neuvonen, Pertti J
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Blackwell Science Inc 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884466/
https://ncbi.nlm.nih.gov/pubmed/15025742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.02027.x
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