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Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration

MicroRNAs (miRNAs) are small noncoding RNAs that can act to repress target mRNAs by suppressing translation and/or reducing mRNA stability. Although it is clear that miRNAs and Dicer, an RNase III enzyme that is central to the production of mature miRNAs, have a role in the early development of neur...

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Autors principals: Cuellar, Trinna L., Davis, Tigwa H., Nelson, Peter T., Loeb, Gabriel B., Harfe, Brian D., Ullian, Erik, McManus, Michael T.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291142/
https://ncbi.nlm.nih.gov/pubmed/18385371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801689105
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