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The microRNA-processing enzyme DICER is dispensable for somite segmentation but essential for limb bud positioning

DICER is an enzyme that processes microRNAs (miRNAs) to their mature forms. As miRNAs were first discovered for their role in the control of developmental timing, we investigated their potential requirement in mouse somitogenesis, an event with precise temporal periodicity. To address the collective...

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Detalhes bibliográficos
Principais autores: Zhang, Zhen, O’Rourke, Jason R., McManus, Michael T., Lewandoski, Mark, Harfe, Brian D., Sun, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541530/
https://ncbi.nlm.nih.gov/pubmed/21256124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.01.005
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