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The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb

The RNaseIII-containing enzyme Dicer is believed to be required for the processing of most, if not all, microRNAs (miRNAs) and for processing long dsRNA into small interfering RNAs. Because the complete loss of Dicer in both zebrafish and mice results in early embryonic lethality, it has been imposs...

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Détails bibliographiques
Auteurs principaux: Harfe, Brian D., McManus, Michael T., Mansfield, Jennifer H., Hornstein, Eran, Tabin, Clifford J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182454/
https://ncbi.nlm.nih.gov/pubmed/16040801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504834102
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