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The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

MicroRNAs (miRNAs) are implicated in the differentiation and function of many cell types. We provide genetic and in vivo evidence that the two RNaseIII enzymes, Drosha and Dicer, do indeed function in the same pathway. These have previously been shown to mediate the stepwise maturation of miRNAs (Le...

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Hlavní autoři: Chong, Mark M.W., Rasmussen, Jeffrey P., Rudensky, Alexander Y., Littman, Dan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526196/
https://ncbi.nlm.nih.gov/pubmed/18725527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081219
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