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The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease
MicroRNAs (miRNAs) are implicated in the differentiation and function of many cell types. We provide genetic and in vivo evidence that the two RNaseIII enzymes, Drosha and Dicer, do indeed function in the same pathway. These have previously been shown to mediate the stepwise maturation of miRNAs (Le...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2526196/ https://ncbi.nlm.nih.gov/pubmed/18725527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081219 |
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