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Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus
To investigate the role of Dicer and microRNAs in the mammalian CNS, we used mice in which the second RNase III domain of Dicer was conditionally floxed. Conditional Dicer mice were bred with mice expressing an α-calmodulin kinase II Cre to selectively inactivate Dicer in excitatory forebrain neuron...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844796/ https://ncbi.nlm.nih.gov/pubmed/18434510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4815-07.2008 |
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