Early memory formation disrupted by atypical PKC inhibitor ZIP in the medial prefrontal cortex but not hippocampus

Atypical isoforms of protein kinase C (aPKCs; particularly protein kinase M zeta: PKMζ) have been hypothesised to be necessary and sufficient for the maintenance of long-term potentiation (LTP) and long term memory by maintaining postsynaptic AMPA receptors via the GluR2 subunit. A myristoylated PKM...

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Detalhes bibliográficos
Publicado no:Hippocampus
Main Authors: Evuarherhe, Obaro, Barker, Gareth R. I., Savalli, Giorgia, Warburton, Elizabeth C., Brown, Malcolm W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285083/
https://ncbi.nlm.nih.gov/pubmed/24729442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.22281
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