DESCENDING SEROTONERGIC FACILITATION OF SPINAL ERK ACTIVATION AND PAIN BEHAVIOR

Serotonin (5-HT) derived from bulbo-spinal projection is released by nociceptive input into the spinal dorsal horn. Here we report that formalin injection in the paw produced pain behavior (flinching) and phosphorylation of spinal ERK1/2 (P-ERK1/2, indicating activation) in rats. Depletion of spinal...

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Detaylı Bibliyografya
Asıl Yazarlar: Svensson, Camilla I., Tran, Thao K., Fitzsimmons, Bethany, Yaksh, Tony L., Hua, Xiao-Ying
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291024/
https://ncbi.nlm.nih.gov/pubmed/17113581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2006.11.012
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