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Central terminal sensitization of TRPV1 by descending serotonergic facilitation modulates chronic pain
The peripheral terminals of primary nociceptive neurons play an essential role in pain detection mediated by membrane receptors like TRPV1, a molecular sensor of heat and capsaicin. However, the contribution of central terminal TRPV1 in the dorsal horn to chronic pain has not been investigated direc...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943838/ https://ncbi.nlm.nih.gov/pubmed/24462040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.12.011 |
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