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Induction of microsatellite instability by oxidative DNA damage

Instability of repetitive sequences, both in intronic sequences and within coding regions, has been demonstrated to be a hallmark of genomic instability in human cancer. Understanding how these mutational events arise may provide an opportunity for prevention or early intervention in cancer developm...

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Detalhes bibliográficos
Main Authors: Jackson, Aimee L., Chen, Ru, Loeb, Lawrence A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22854/
https://ncbi.nlm.nih.gov/pubmed/9770509
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