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Oxidative DNA Damage Causes Mitochondrial Genomic Instability in Saccharomyces cerevisiae
Mitochondria contain their own genome, the integrity of which is required for normal cellular energy metabolism. Reactive oxygen species (ROS) produced by normal mitochondrial respiration can damage cellular macromolecules, including mitochondrial DNA (mtDNA), and have been implicated in degenerativ...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2005
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1140570/ https://ncbi.nlm.nih.gov/pubmed/15923634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.12.5196-5204.2005 |
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