Checkpoint kinase phosphorylation in response to endogenous oxidative DNA damage in repair-deficient stationary-phase Saccharomyces cerevisiae

Stationary phase Saccharomyces cerevisiae can serve as a model for postmitotic cells of higher eukaryotes. Phosphorylation and activation of the checkpoint kinase Rad53 was observed after more than 2 days of culture if two major pathways of oxidative DNA damage repair, base excision repair (BER) and...

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Bibliographic Details
Main Authors: Pawar, Vaibhav, Jingjing, Liu, Patel, Nila, Kaur, Nimrat, Doetsch, Paul W., Shadel, Gerald S., Zhang, Hong, Siede, Wolfram
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716406/
https://ncbi.nlm.nih.gov/pubmed/19540258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2009.06.002
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