The Conserved Mec1/Rad53 Nuclear Checkpoint Pathway Regulates Mitochondrial DNA Copy Number in Saccharomyces cerevisiae

How mitochondrial DNA (mtDNA) copy number is determined and modulated according to cellular demands is largely unknown. Our previous investigations of the related DNA helicases Pif1p and Rrm3p uncovered a role for these factors and the conserved Mec1/Rad53 nuclear checkpoint pathway in mtDNA mutagen...

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Detaylı Bibliyografya
Asıl Yazarlar: Taylor, Sean D., Zhang, Hong, Eaton, Jana S., Rodeheffer, Matthew S., Lebedeva, Maria A., O'Rourke, Thomas W., Siede, Wolfram, Shadel, Gerald S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2005
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142443/
https://ncbi.nlm.nih.gov/pubmed/15829566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-01-0053
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