The Conserved Mec1/Rad53 Nuclear Checkpoint Pathway Regulates Mitochondrial DNA Copy Number in Saccharomyces cerevisiae

How mitochondrial DNA (mtDNA) copy number is determined and modulated according to cellular demands is largely unknown. Our previous investigations of the related DNA helicases Pif1p and Rrm3p uncovered a role for these factors and the conserved Mec1/Rad53 nuclear checkpoint pathway in mtDNA mutagen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Taylor, Sean D., Zhang, Hong, Eaton, Jana S., Rodeheffer, Matthew S., Lebedeva, Maria A., O'Rourke, Thomas W., Siede, Wolfram, Shadel, Gerald S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2005
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142443/
https://ncbi.nlm.nih.gov/pubmed/15829566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-01-0053
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