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The CBS subdomain of inosine 5’-monophosphate dehydrogenase regulates purine nucleotide turnover
Inosine 5’-monophosphate dehydrogenase (IMPDH) catalyzes the rate limiting step in guanine nucleotide biosynthesis. IMPDH has an evolutionary conserved CBS subdomain of unknown function. The subdomain can be deleted without impairing the in vitro IMPDH catalytic activity and is the site for mutation...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279236/ https://ncbi.nlm.nih.gov/pubmed/18312263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06153.x |
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