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Structure of Pseudomonas aeruginosa inosine 5′-monophosphate dehydrogenase

Inosine 5′-monophosphate dehydrogenase (IMPDH) represents a potential antimicrobial drug target. The crystal structure of recombinant Pseudomonas aeruginosa IMPDH has been determined to a resolution of 2.25 Å. The structure is a homotetramer of subunits dominated by a (β/α)(8)-barrel fold, consisten...

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Detalhes bibliográficos
Main Authors: Rao, Vincenzo A., Shepherd, Sharon M., Owen, Richard, Hunter, William N.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606566/
https://ncbi.nlm.nih.gov/pubmed/23519796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113002352
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