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Somatostatin inhibits exocytosis in rat pancreatic α-cells by G(i2)-dependent activation of calcineurin and depriming of secretory granules
1. Measurements of cell capacitance were used to investigate the molecular mechanisms by which somatostatin inhibits Ca(2+)-induced exocytosis in single rat glucagon-secreting pancreatic α-cells. 2. Somatostatin decreased the exocytotic responses elicited by voltage-clamp depolarisations by 80 % in...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278803/ https://ncbi.nlm.nih.gov/pubmed/11533141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.00519.x |
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