GABA(B) receptor activation inhibits exocytosis in rat pancreatic β-cells by G-protein-dependent activation of calcineurin

We have investigated the regulation of hormone secretion from rat pancreatic islets by the GABA(B) receptors (GABA(B)Rs). Inclusion of the specific GABA(B)R antagonist CGP 55845 in the extracellular medium increased glucose-stimulated insulin secretion 1.6-fold but did not affect the release of gluc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Braun, Matthias, Wendt, Anna, Buschard, Karsten, Salehi, Albert, Sewing, Sabine, Gromada, Jesper, Rorsman, Patrik
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2004
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665126/
https://ncbi.nlm.nih.gov/pubmed/15235087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.066563
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