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Regulated Exocytosis of GABA-containing Synaptic-like Microvesicles in Pancreatic β-cells

We have explored whether γ-aminobutyric acid (GABA) is released by regulated exocytosis of GABA-containing synaptic-like microvesicles (SLMVs) in insulin-releasing rat pancreatic β-cells. To this end, β-cells were engineered to express GABA(A)-receptor Cl(−)-channels at high density using adenoviral...

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Hlavní autoři: Braun, Matthias, Wendt, Anna, Birnir, Bryndis, Broman, Jonas, Eliasson, Lena, Galvanovskis, Juris, Gromada, Jesper, Mulder, Hindrik, Rorsman, Patrik
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217446/
https://ncbi.nlm.nih.gov/pubmed/14769845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200308966
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