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Pregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the α subunit
1. Neurosteroids are produced in the brain, and can have rapid actions on membrane channels of neurons. Pregnenolone sulfate (PS) is a sulfated neurosteroid which reduces the responses of the γ-aminobutyric acid A (GABAA) receptor. We analysed the actions of PS on single-channel currents from recomb...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Science Inc
2001
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278584/ https://ncbi.nlm.nih.gov/pubmed/11313438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.0673e.x |
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