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Synthesis and In Vitro Anti-Leukemic Activity of Structural Analogues of JS-K, an Anti-Cancer Lead Compound

Structural analogues of JS-K, an anti-cancer lead compound, were prepared and their in vitro anti-leukemic activity was determined. The rate of nitric oxide release from the corresponding diazeniumdiolate anions did not appear to affect the anti-leukemic activity of the prodrug forms. Two compounds...

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Detalhes bibliográficos
Main Authors: Chakrapani, Harinath, Goodblatt, Michael M., Udupi, Vidya, Malaviya, Swati, Shami, Paul J., Keefer, Larry K., Saavedra, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278236/
https://ncbi.nlm.nih.gov/pubmed/18178089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.12.044
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