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Regulation of the proapoptotic factor Bax by Ku70-dependent deubiquitylation
The DNA end-joining protein Ku70 is one of several proteins that inhibit apoptosis by sequestering the proapoptotic factor Bax from the mitochondria. However, the molecular mechanism underlying Ku70-dependent inhibition of Bax is not fully understood. Here, we show that the absence of Ku70 results i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278173/ https://ncbi.nlm.nih.gov/pubmed/18362350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706700105 |
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