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Interaction of a Cyclin E Fragment with Ku70 Regulates Bax-Mediated Apoptosis

The cyclin E/Cdk2 complex plays an essential role in the G(1)/S cell cycle transition and DNA replication. Earlier we showed that in hematopoietic tumor cells, caspase-mediated cleavage of cyclin E generates p18-cyclin E, which is unable to interact with Cdk2 and therefore plays a role independent o...

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Détails bibliographiques
Auteurs principaux: Mazumder, Suparna, Plesca, Dragos, Kinter, Michael, Almasan, Alexandru
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899959/
https://ncbi.nlm.nih.gov/pubmed/17325036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01448-06
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