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Interaction of a Cyclin E Fragment with Ku70 Regulates Bax-Mediated Apoptosis
The cyclin E/Cdk2 complex plays an essential role in the G(1)/S cell cycle transition and DNA replication. Earlier we showed that in hematopoietic tumor cells, caspase-mediated cleavage of cyclin E generates p18-cyclin E, which is unable to interact with Cdk2 and therefore plays a role independent o...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1899959/ https://ncbi.nlm.nih.gov/pubmed/17325036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01448-06 |
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