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Interaction of Caveolin-1 with Ku70 Inhibits Bax-Mediated Apoptosis
Caveolin-1, the structural protein component of caveolae, acts as a scaffolding protein that functionally regulates signaling molecules. We show that knockdown of caveolin-1 protein expression enhances chemotherapeutic drug-induced apoptosis and inhibits long-term survival of colon cancer cells. In...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380016/ https://ncbi.nlm.nih.gov/pubmed/22745744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039379 |
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