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Interaction of Caveolin-1 with Ku70 Inhibits Bax-Mediated Apoptosis

Caveolin-1, the structural protein component of caveolae, acts as a scaffolding protein that functionally regulates signaling molecules. We show that knockdown of caveolin-1 protein expression enhances chemotherapeutic drug-induced apoptosis and inhibits long-term survival of colon cancer cells. In...

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Detalhes bibliográficos
Main Authors: Zou, Huafei, Volonte, Daniela, Galbiati, Ferruccio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380016/
https://ncbi.nlm.nih.gov/pubmed/22745744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039379
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