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Inhibition of thioredoxin reductase 1 by caveolin 1 promotes stress-induced premature senescence
Thioredoxin reductase 1 (TrxR1) is an important antioxidant enzyme that controls cellular redox homeostasis. By using a proteomic-based approach, here we identify TrxR1 as a caveolar membrane-resident protein. We show that caveolin 1, the structural protein component of caveolae, is a TrxR1-binding...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799211/ https://ncbi.nlm.nih.gov/pubmed/19820694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.215 |
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