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Expression of Caveolin-1 Induces Premature Cellular Senescence in Primary Cultures of Murine Fibroblasts: Stress-Induced Premature Senescence Upregulates the Expression of Endogenous Caveolin-1

Caveolae are vesicular invaginations of the plasma membrane. Caveolin-1 is the principal structural component of caveolae in vivo. Several lines of evidence are consistent with the idea that caveolin-1 functions as a “transformation suppressor” protein. In fact, caveolin-1 mRNA and protein expressio...

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Detalhes bibliográficos
Main Authors: Volonte, Daniela, Zhang, Kun, Lisanti, Michael P., Galbiati, Ferruccio
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117330/
https://ncbi.nlm.nih.gov/pubmed/12134086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-11-0529
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