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MgATP activates the β cell K(ATP )channel by interaction with its SUR1 subunit
ATP-sensitive potassium (K(ATP)) channels in the pancreatic β cell membrane mediate insulin release in response to elevation of plasma glucose levels. They are open at rest but close in response to glucose metabolism, producing a depolarization that stimulates Ca(2+) influx and exocytosis. Metabolic...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The National Academy of Sciences
1998
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC22779/ https://ncbi.nlm.nih.gov/pubmed/9618560 |
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