Flurazepam effect on GABAergic currents depends on extracellular pH

BACKGROUND AND PURPOSE: Benzodiazepines (BDZs) are widely used in clinical practice and are known as positive modulators of GABAergic currents. BDZs increase binding affinity and recently they were found to affect GABA(A) receptor gating, including desensitization. Binding and desensitization are al...

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Библиографические подробности
Главные авторы: Wójtowicz, T, Wyrembek, P, Lebida, K, Piast, M, Mozrzymas, J W
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2008
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Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276312/
https://ncbi.nlm.nih.gov/pubmed/18362897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.90
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