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Flurazepam effect on GABAergic currents depends on extracellular pH
BACKGROUND AND PURPOSE: Benzodiazepines (BDZs) are widely used in clinical practice and are known as positive modulators of GABAergic currents. BDZs increase binding affinity and recently they were found to affect GABA(A) receptor gating, including desensitization. Binding and desensitization are al...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276312/ https://ncbi.nlm.nih.gov/pubmed/18362897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.90 |
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