Flurazepam effect on GABAergic currents depends on extracellular pH

BACKGROUND AND PURPOSE: Benzodiazepines (BDZs) are widely used in clinical practice and are known as positive modulators of GABAergic currents. BDZs increase binding affinity and recently they were found to affect GABA(A) receptor gating, including desensitization. Binding and desensitization are al...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Wójtowicz, T, Wyrembek, P, Lebida, K, Piast, M, Mozrzymas, J W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276312/
https://ncbi.nlm.nih.gov/pubmed/18362897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.90
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi