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The Programmed Cell Death of an Immature Thymocyte Cell Line Transgenic for an αβ TCR and the c-myc Proto-Oncogene

The c-myc proto-oncogene linked to the mouse Thy-1 gene transcriptional unit predisposes mice to development of thymic tumors consisting predominantly of immature CD4(+) CD8(+) cells. In an attempt to immortalize immature T cells expressing a known T-cell antigen receptor (TCR), Thy-1/c-myc transgen...

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Detalles Bibliográficos
Main Authors: Murdjeva, Marianna, Tanaka, Yujiro, Norton, Trisha, Kioussis, Dimitris
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275968/
https://ncbi.nlm.nih.gov/pubmed/8924763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1995/93271
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