Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms

BACKGROUND: Thyroid receptors, TRα and TRβ, are involved in important physiological functions such as metabolism, cholesterol level and heart activities. Whereas metabolism increase and cholesterol level lowering could be achieved by TRβ isoform activation, TRα activation affects heart rates. Theref...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bleicher, Lucas, Aparicio, Ricardo, Nunes, Fabio M, Martinez, Leandro, Gomes Dias, Sandra M, Figueira, Ana Carolina Migliorini, Santos, Maria Auxiliadora Morim, Venturelli, Walter H, da Silva, Rosangela, Donate, Paulo Marcos, Neves, Francisco AR, Simeoni, Luiz A, Baxter, John D, Webb, Paul, Skaf, Munir S, Polikarpov, Igor
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275733/
https://ncbi.nlm.nih.gov/pubmed/18237438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-8-8
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky