Interference with PPARγ Function in Smooth Muscle Causes Vascular Dysfunction and Hypertension

Peroxisome proliferator-activated receptor-γ (PPARγ) is a ligand activated transcription factor playing a critical role in metabolism. Thiazolidinediones, high affinity PPARγ ligands used clinically to treat type-II diabetes, have been reported to lower blood pressure and provide other cardiovascula...

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Autores principales: Halabi, Carmen M., Beyer, Andreas M., de Lange, Willem J., Keen, Henry L., Baumbach, Gary L., Faraci, Frank M., Sigmund, Curt D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275166/
https://ncbi.nlm.nih.gov/pubmed/18316027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.12.008
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