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Interference with PPARγ in Vascular Smooth Muscle Causes Baroreflex Impairment and Autonomic Dysfunction
S-P467L mice expressing dominant negative Peroxisome Proliferator Activated Receptor-γ selectively in vascular smooth muscle, exhibit impaired vasodilation, augmented vasoconstriction, hypertension and tachycardia. We hypothesized that tachycardia in S-P467L mice is due to baroreflex dysfunction. S-...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134389/ https://ncbi.nlm.nih.gov/pubmed/24914194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03553 |
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