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A Hypertension-causing Mutation in PPARγ Impairs Nuclear Export of NF-κB p65 in Vascular Smooth Muscle
Selective expression of dominant negative (DN) peroxisome proliferator-activated receptor gamma (PPARγ) in vascular smooth muscle cells (SMC) results in hypertension, atherosclerosis, and increased NF-κB target gene expression. Mesenteric SMC were cultured from mice designed to conditionally express...
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| Published in: | Hypertension |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5472224/ https://ncbi.nlm.nih.gov/pubmed/28507170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09276 |
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