A Hypertension-causing Mutation in PPARγ Impairs Nuclear Export of NF-κB p65 in Vascular Smooth Muscle

Selective expression of dominant negative (DN) peroxisome proliferator-activated receptor gamma (PPARγ) in vascular smooth muscle cells (SMC) results in hypertension, atherosclerosis, and increased NF-κB target gene expression. Mesenteric SMC were cultured from mice designed to conditionally express...

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Pubblicato in:Hypertension
Autori principali: Mukohda, Masashi, Lu, Ko-Ting, Guo, Deng-Fu, Wu, Jing, Keen, Henry L., Liu, Xuebo, Ketsawatsomkron, Pimonrat, Stump, Madeliene, Rahmouni, Kamal, Quelle, Frederick W., Sigmund, Curt D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472224/
https://ncbi.nlm.nih.gov/pubmed/28507170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09276
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