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Interference with PPARγ Function in Smooth Muscle Causes Vascular Dysfunction and Hypertension
Peroxisome proliferator-activated receptor-γ (PPARγ) is a ligand activated transcription factor playing a critical role in metabolism. Thiazolidinediones, high affinity PPARγ ligands used clinically to treat type-II diabetes, have been reported to lower blood pressure and provide other cardiovascula...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275166/ https://ncbi.nlm.nih.gov/pubmed/18316027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.12.008 |
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