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Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA

The tumour suppressor p53 is a transcription factor that binds DNA in the vicinity of the genes it controls. The affinity of p53 for specific binding sites relative to other DNA sequences is an inherent driving force for specificity, all other things being equal. We measured the binding affinities o...

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Bibliografski detalji
Glavni autori: Veprintsev, Dmitry B., Fersht, Alan R.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275157/
https://ncbi.nlm.nih.gov/pubmed/18234719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1040
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