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14-3-3 activation of DNA binding of p53 by enhancing its association into tetramers
Activation of the tumour suppressor p53 on DNA damage involves post-translational modification by phosphorylation and acetylation. Phosphorylation of certain residues is critical for p53 stabilization and plays an important role in DNA-binding activity. The 14-3-3 family of proteins activates the DN...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Oxford University Press
2008
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2566891/ https://ncbi.nlm.nih.gov/pubmed/18812399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn598 |
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