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Mechanistic differences in the transcriptional activation of p53 by 14-3-3 isoforms
p53 maintains genome integrity by initiating the transcription of genes involved in cell-cycle arrest, senescence, apoptosis and DNA repair. The activity of p53 is regulated by both post-translational modifications and protein–protein interactions. p53 that has been phosphorylated at S366, S378 and...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2817464/ https://ncbi.nlm.nih.gov/pubmed/19933256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1041 |
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