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FRET studies with Factor X mutants provide insight into the topography of the membrane-bound Factor X/Xa

FRET (fluorescence resonance energy transfer) studies have shown that the vitamin K-dependent coagulation proteases bind to membrane surfaces perpendicularly, positioning their active sites above the membrane surfaces. To investigate whether EGF (epidermal growth factor) domains of these proteases p...

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Autori principali: Qureshi, Shabir H., Yang, Likui, Yegneswaran, Subramanian, Rezaie, Alireza R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275069/
https://ncbi.nlm.nih.gov/pubmed/17635109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070735
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