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HOIL-1 is not required for iron-mediated IRP2 degradation in HEK293 cells
Iron regulatory protein 2 (IRP2) binds to iron-responsive elements (IREs) in the mRNAs encoding several proteins involved in mammalian iron homeostasis to regulate their translation and stability. Increases in cellular iron content stimulate the polyubiquitylation and proteasomal degradation of IRP2...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2274887/ https://ncbi.nlm.nih.gov/pubmed/17822790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2007.07.010 |
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