Iron-independent Phosphorylation of Iron Regulatory Protein 2 Regulates Ferritin during the Cell Cycle

Iron regulatory protein 2 (IRP2) is a key iron sensor that post-transcriptionally regulates mammalian iron homeostasis by binding to iron-responsive elements (IREs) in mRNAs that encode proteins involved in iron metabolism (e.g. ferritin and transferrin receptor 1). During iron deficiency, IRP2 bind...

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Xehetasun bibliografikoak
Egile Nagusiak: Wallander, Michelle L., Zumbrennen, Kimberly B., Rodansky, Eva S., Romney, S. Joshua, Leibold, Elizabeth A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Protein Synthesis, Post-Translational Modification, and Degradation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527096/
https://ncbi.nlm.nih.gov/pubmed/18574241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803005200
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