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Cysteine Oxidation Regulates the RNA-Binding Activity of Iron Regulatory Protein 2

Iron regulatory protein 2 (IRP2) is an RNA-binding protein that regulates the posttranscriptional expression of proteins required for iron homeostasis such as ferritin and transferrin receptor 1. IRP2 RNA-binding activity is primarily regulated by iron-mediated proteasomal degradation, but studies h...

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Detalhes bibliográficos
Main Authors: Zumbrennen, Kimberly B., Wallander, Michelle L., Romney, S. Joshua, Leibold, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663299/
https://ncbi.nlm.nih.gov/pubmed/19223469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00004-09
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