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Structure–function analysis of vaccinia virus mRNA cap (guanine-N7) methyltransferase

The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Structure–function analysis of the catalytic subunit by alanine scanning and conservative substitutions (49 mutations at 25 amino acids) identifie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zheng, Sushuang, Shuman, Stewart
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271365/
https://ncbi.nlm.nih.gov/pubmed/18256245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.928208
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