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Structural insights into the mechanism and evolution of the vaccinia virus mRNA cap N7 methyl-transferase

The vaccinia virus mRNA capping enzyme is a multifunctional heterodimeric protein associated with the viral polymerase that both catalyses the three steps of mRNA capping and regulates gene transcription. The structure of a subcomplex comprising the C-terminal N7-methyl-transferase (MT) domain of th...

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Autori principali: De la Peña, Marcos, Kyrieleis, Otto J P, Cusack, Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099473/
https://ncbi.nlm.nih.gov/pubmed/17989694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601912
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