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Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

Tumor necrosis factor (TNF) is key to the pathogenesis of various arthritic diseases and inflammatory bowel disease (IBD). Anti-TNF therapies have proved successful in the clinical treatment of these diseases, but a mechanistic understanding of TNF function is still lacking. We have investigated ear...

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Detalhes bibliográficos
Main Authors: Armaka, Maria, Apostolaki, Maria, Jacques, Peggy, Kontoyiannis, Dimitris L., Elewaut, Dirk, Kollias, George
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271010/
https://ncbi.nlm.nih.gov/pubmed/18250193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070906
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