Comorbid TNF-mediated heart valve disease and chronic polyarthritis share common mesenchymal cell-mediated aetiopathogenesis

OBJECTIVES: Patients with rheumatoid arthritis and spondyloarthritisshow higher mortality rates, mainly caused by cardiac comorbidities. The TghuTNF (Tg197) arthritis model develops tumour necrosis factor (TNF)-driven and mesenchymalsynovial fibroblast (SF)-dependent polyarthritis. Here, we investig...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Ntari, Lydia, Sakkou, Maria, Chouvardas, Panagiotis, Mourouzis, Iordanis, Prados, Alejandro, Denis, Maria C, Karagianni, Niki, Pantos, Constantinos, Kollias, George
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Basic and Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965351/
https://ncbi.nlm.nih.gov/pubmed/29475857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2017-212597
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