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Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis

Mesenchymal TNF signaling is etiopathogenic for inflammatory diseases such as rheumatoid arthritis and spondyloarthritis (SpA). The role of Tnfr1 in arthritis has been documented; however, Tnfr2 functions are unknown. Here, we investigate the mesenchymal-specific role of Tnfr2 in the Tnf(ΔARE) mouse...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Sakkou, Maria, Chouvardas, Panagiotis, Ntari, Lydia, Prados, Alejandro, Moreth, Kristin, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Denis, Maria C., Karagianni, Niki, Kollias, George
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928856/
https://ncbi.nlm.nih.gov/pubmed/29618659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98864
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