Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis

Mesenchymal TNF signaling is etiopathogenic for inflammatory diseases such as rheumatoid arthritis and spondyloarthritis (SpA). The role of Tnfr1 in arthritis has been documented; however, Tnfr2 functions are unknown. Here, we investigate the mesenchymal-specific role of Tnfr2 in the Tnf(ΔARE) mouse...

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Detalles Bibliográficos
Publicado en:JCI Insight
Main Authors: Sakkou, Maria, Chouvardas, Panagiotis, Ntari, Lydia, Prados, Alejandro, Moreth, Kristin, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabe de Angelis, Martin, Denis, Maria C., Karagianni, Niki, Kollias, George
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928856/
https://ncbi.nlm.nih.gov/pubmed/29618659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98864
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