Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis

BACKGROUND: The transmembrane-TNF transgenic mouse, TgA86, has been shown to develop spontaneously peripheral arthritis with signs of axial involvement. To assess similarity to human spondyloarthritis, we performed detailed characterization of the axial, peripheral, and comorbid pathologies of this...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Christodoulou-Vafeiadou, Eleni, Geka, Christina, Ntari, Lydia, Kranidioti, Ksanthi, Argyropoulou, Eleni, Meier, Florian, Armaka, Marietta, Mourouzis, Iordanis, Pantos, Constantinos, Rouchota, Maritina, Loudos, George, Denis, Maria C., Karagianni, Niki, Kollias, George
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7542121/
https://ncbi.nlm.nih.gov/pubmed/33023659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02327-4
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