Attenuation of TNF-driven murine ileitis by intestinal expression of the viral immunomodulator CrmD

Tumor necrosis factor α (TNFα) is a key pathogenic factor in Crohn’s disease and rheumatoid arthritis. TNF(ΔARE) mice express high levels of TNFα and present Crohn’s-like ileitis and arthritis. Alterations in the chemokine network could underline the TNF-driven ileitis. The aim of this study was to...

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Autors principals: Viejo-Borbolla, Abel, Martin, Andrea P., Muniz, Luciana R., Shang, Limin, Marchesi, Federica, Thirunarayanan, Nanthakumar, Harpaz, Noam, Garcia, Roberto A., Apostolaki, Maria, Furtado, Glaucia C., Mayer, Lloyd, Kollias, George, Alcami, Antonio, Lira, Sergio A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2979317/
https://ncbi.nlm.nih.gov/pubmed/20664576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2010.40
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