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p27 Deficiency Cooperates with Bcl-2 but Not Bax to Promote T-Cell Lymphoma

The effect of Bcl-2 on oncogenesis is complex and expression may either delay or accelerate oncogenesis. The pro-oncogenic activity is attributed to its well characterized anti-apoptotic function while the anti-oncogenic function has been attributed to its inhibition of cellular proliferation. Recen...

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Detalhes bibliográficos
Main Authors: Cheng, Ningli, van de Wetering, Christopher I., Knudson, C. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270898/
https://ncbi.nlm.nih.gov/pubmed/18382684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001911
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